Acetyl-L-Carnitine 500 mg Bioavailability Study
Bioavailability Study
Acetyl-L-Carnitine is a modified amino acid that supports cellular energy production by assisting in the transport of fat into the mitochondria, where it is oxidized and converted into ATP.*
Three healthy adult volunteers, 22 to 55 years old, participated in a clinical trial to study the bioavailability of Acetyl L-Carnitine 500 mg, a dietary supplement from NOW® (# 0076). Total serum carnitine was measured at baseline, and again at 1, 3, and 6 hours following oral administration of 2 capsules providing 1 gram (1,000 mg) of acetyl-L-carnitine.
Results
Average serum carnitine peaked three hours after supplement administration, reaching 25% over the baseline level. Six hours post-supplementation, average carnitine concentration remained elevated 20% over the baseline level. This study confirms the exceptional bioavailability of NOW® Acetyl-L-Carnitine 500 mg Veg Caps from NOW®.
Time, hours
Total serum carnitine, µmol/L
0
46.0
1
51.0
2
55.0
3
58.5
4
58.5
5
57.5
6
56.0
Average total serum carnitine level before, and 1, 3, and 6 hours following a single administration of two Acetyl-L-Carnitine 500 mg Veg Capsules (NOW®, Bloomingdale, Illinois; #0076) providing 1,000 mg of acetyl-L-carnitine in healthy adult volunteers.
*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.
