MK-7 Vitamin K-2 100 mcg - Pharmacokinetic (pK) Study
Bioavailability Study
MK-7 is a form of vitamin K-2 that plays a role in the synthesis of blood coagulation factors, bone health, and the maintenance of vascular elasticity.* Three healthy adult volunteers 28 to 52 years old participated in a clinical trial to study the bioavailability of MK-7, a dietary supplement from NOW® (item # 0992). Plasma vitamin K was measured at baseline, and again at 4, 6 and 24 hours following oral administration of one capsule providing 100 mcg of NOW® MK-7.
Results
Average vitamin K increased four hours after administration, and peaked six hours following administration, reaching 41% above the baseline level. Average vitamin K concentration returned to near-baseline level 24 hours post-supplementation. This study confirms the exceptional bioavailability of NOW® MK-7.
Average vitamin K concentrations following a single administration of 100 mg Menaquinone-7 (MK-7, NOW Foods, Product #0992) in healthy adult volunteers. 
Time, hours
Serum Vitamin K, pg/mL
0
570
2
655
4
760
6
800
8
780
10
755
12
745
14
720
16
675
18
650
20
640
22
625
24
600
*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.
