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ACTION to receive $30 off $110+ order†Biotin 5000 mcg - Pharmacokinetic (pK) Study
Bioavailability Study
Dietary supplement Biotin is a water-soluble vitamin necessary for normal growth and body function, and as a key regulatory element in gluconeogenesis, fatty acid synthesis, and in the metabolism of some amino acids.* Three healthy adult volunteers 25-55 years old participated in a clinical trial to study the bioavailability of Biotin, a dietary supplement by NOW® Foods (# 0471). Serum biotin was measured at baseline, and 2, 4, and 24 hours following oral administration of 1 capsule providing 5,000 mcg of Biotin.
Results
The average serum biotin peaked 2 hours following the administration, reaching 625% above the baseline level. The average biotin concentration remained elevated for the duration of the study and remained 187% above the baseline levels 24 hours post-supplementation. The study confirms the exceptional bioavailability of the dietary supplement Biotin by NOW®.
| Time, hours | Serum biotin pg/mL |
|---|---|
| 0 | 1600 |
| 2 | 8500 |
| 4 | 8000 |
| 6 | 7750 |
| 8 | 7000 |
| 10 | 6500 |
| 12 | 6000 |
| 14 | 5750 |
| 16 | 5000 |
| 18 | 4750 |
| 20 | 4500 |
| 22 | 4000 |
| 24 | 3000 |
Average serum biotin levels before, and 2, 4 and 24 hours following a single administration of one capsule of Biotin 5,000 mcg (NOW® Foods, Bloomingdale, IL; Product #0471) in healthy adult volunteers.
*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.
