Biotin 5000 mcg - Pharmacokinetic (pK) Study
Bioavailability Study
Dietary supplement Biotin is a water-soluble vitamin necessary for normal growth and body function, and as a key regulatory element in gluconeogenesis, fatty acid synthesis, and in the metabolism of some amino acids.* Three healthy adult volunteers 25-55 years old participated in a clinical trial to study the bioavailability of Biotin, a dietary supplement by NOW® Foods (# 0471). Serum biotin was measured at baseline, and 2, 4, and 24 hours following oral administration of 1 capsule providing 5,000 mcg of Biotin.
Results
The average serum biotin peaked 2 hours following the administration, reaching 625% above the baseline level. The average biotin concentration remained elevated for the duration of the study and remained 187% above the baseline levels 24 hours post-supplementation. The study confirms the exceptional bioavailability of the dietary supplement Biotin by NOW®.
Time, hours
Serum biotin pg/mL
0
1600
2
8500
4
8000
6
7750
8
7000
10
6500
12
6000
14
5750
16
5000
18
4750
20
4500
22
4000
24
3000
Average serum biotin levels before, and 2, 4 and 24 hours following a single administration of one capsule of Biotin 5,000 mcg (NOW® Foods, Bloomingdale, IL; Product #0471) in healthy adult volunteers.
*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.
